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M10 (TRPASFWETS)

M10 (TRPASFWETS)

$ 100.00 MXN
$ 100.00 MXN
Oferta Agotado
Impuestos incluidos.
Grade
FOR RESEARCH AND LABORATORY USE ONLY
Material intended exclusively for scientific and in vitro research. Not for human, clinical, or medical use.

M10 (TRPASFWETS) — Research Peptide


M10 is a synthetic 10-amino-acid peptide sequence (Thr-Arg-Pro-Ala-Ser-Phe-Trp-Glu-Thr-Ser) derived from the intracellular cytoplasmic tail of the hepatocyte growth factor receptor (c-MET/MET) following cleavage by caspase-3. This high-purity reagent is used in preclinical laboratory environments to investigate tissue remodeling, extracellular matrix regulation, and TGF-β/Smad signaling pathways.


Technical Specifications Details
Sequence Thr-Arg-Pro-Ala-Ser-Phe-Trp-Glu-Thr-Ser (TRPASFWETS)
Molecular Formula $\text{C}_{53}\text{H}_{76}\text{N}_{14}\text{O}_{17}$
Molecular Weight 1181.25 g/mol
Purity $\ge 98.0\%$ (Verified by HPLC)
Physical Appearance Sterile, lyophilized white powder
Origin Endogenous c-MET receptor fragment

Key Features & Research Applications

Target Binding Studies: Evaluated for its binding interactions with the MH2 domain of Smad2, inhibiting downstream TGF-β-induced Smad2 phosphorylation in vitro.

Preclinical Assays: Investigated for suppressing fibrotic marker expression, collagen deposition, and connective tissue growth factor (CTGF) in fibroblast cultures.

High Analytical Quality: Verified via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm sequence precision.


Storage & Handling Guidelines

Reconstitution: Dissolve in sterile analytical solvents or bacteriostatic water inside a certified laminar flow hood.

Storage (Unopened): Store dry at 2°C to 8°C for short-term preservation or -20°C for extended shelf life.

Storage (Reconstituted): Maintain liquid aliquots between 2°C to 8°C and minimize freeze-thaw cycles.

What Scientific Evidence Supports

BADGE: GRADE A / B / C ] Preclinical Evidence Framework / Evaluated

Scientific publications and preclinical data associated with this compound focus on the following assay parameters:

Characterization of the mechanism of action on target receptors

Evaluation of metabolic responses and cellular signaling in vitro

Analysis of purity, structural stability, and binding affinity

Supplier Statement

Mechanism declared by BIOPEP Laboratorio:

⚠️ Disclaimer Note:

The above information corresponds exclusively to statements from the manufacturer BIOPEP and has not been independently verified by Peptides Vallarta.

Regulatory Status & Classification

Product Classification: Strictly categorized as a Laboratory Research Chemical / Reagent (Research Use Only - RUO).

COFEPRIS & FDA Status: This compound has not been evaluated, approved, or registered by COFEPRIS (Mexico), the U.S. FDA, or any other global health agency for human therapeutic use, clinical diagnosis, or disease prevention.

Scope of Sale: Available exclusively as an analytical reference material for laboratory experimentation and in vitro bioassays.

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📚 SCIENTIFIC LITERATURE & CITATIONS

  • Journal of Peptide Science.

    Preclinical evaluation of synthetic peptide sequences in cellular membrane receptor binding assays.

  • Analytical Biochemistry

    Analytical characterization and mass spectrometric profiling of synthesized oligopeptides.

  • International Journal of Pharmaceutics

    In vitro stability metrics and structural analysis of lyophilized peptide reagents

⚠️ RESEARCH USE DISCLAIMER

This product is sold exclusively for laboratory research purposes, development of in vitro assays, and scientific analysis.

• NOT FIT FOR HUMAN OR VETERINARY CONSUMPTION.
• NOT A MEDICATION, DRUG, MEDICAL DEVICE, OR THERAPEUTIC PRODUCT.
• PROHIBITED FOR USE IN DIAGNOSIS, TREATMENT, OR PREVENTION OF DISEASES.

The buyer acknowledges and agrees that they are responsible for the safe handling, storage, and disposal of this material in compliance with applicable local regulations.

FREQUENTLY ASKED QUESTIONS

1. What is the format and composition of this product?

This product is supplied in freeze-dried form in a glass vial with the exact purity and quantity indicated in the technical specifications on the label. All components are intended strictly for laboratory analysis and research.

2. How should this material be stored in the laboratory?

To maintain the stability of the material, it is recommended to store the lyophilized vial in a dry environment protected from light at refrigerated temperatures (2–8°C) for short-term storage, or frozen (-20°C) for long-term storage.

3. How can I view the Certificate of Analysis (COA) for my batch?

Each batch comes with quality documentation and traceability reports. You can request or view the Certificate of Analysis (COA), purity data, and endotoxin results for your specific batch number through our Quality and Documentation section or by contacting our support team.

4. How is shipping handled to ensure the product remains intact?

All orders are packaged in accordance with temperature control and cold chain protocols to ensure that the stability of the freeze-dried compound is not compromised during domestic transit.

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