{"product_id":"m10-trpasfwets","title":"M10 (TRPASFWETS)","description":"\u003cp class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color stronger tutor-markdown-rendering\" id=\"model-response-message-contentr_b93dde1e91bc26b8\" dir=\"ltr\"\u003e\u003c\/p\u003e\n\u003cdiv\u003e\u003cb\u003eM10 (TRPASFWETS) — Research Peptide\u003c\/b\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cdiv\u003eM10 is a synthetic 10-amino-acid peptide sequence (\u003cb\u003eThr-Arg-Pro-Ala-Ser-Phe-Trp-Glu-Thr-Ser\u003c\/b\u003e) derived from the intracellular cytoplasmic tail of the hepatocyte growth factor receptor (c-MET\/MET) following cleavage by caspase-3. This high-purity reagent is used in preclinical laboratory environments to investigate tissue remodeling, extracellular matrix regulation, and TGF-β\/Smad signaling pathways.\u003c\/div\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eTechnical Specifications\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003eDetails\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cb\u003eSequence\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eThr-Arg-Pro-Ala-Ser-Phe-Trp-Glu-Thr-Ser (TRPASFWETS)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cb\u003eMolecular Formula\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cspan class=\"math-inline\"\u003e$\\text{C}_{53}\\text{H}_{76}\\text{N}_{14}\\text{O}_{17}$\u003c\/span\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cb\u003eMolecular Weight\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e1181.25 g\/mol\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cb\u003ePurity\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cspan class=\"math-inline\"\u003e$\\ge 98.0\\%$\u003c\/span\u003e (Verified by HPLC)\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cb\u003ePhysical Appearance\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eSterile, lyophilized white powder\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cspan\u003e\u003cb\u003eOrigin\u003c\/b\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan\u003eEndogenous c-MET receptor fragment\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cdiv\u003e\n\u003cb\u003e\u003c\/b\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cp\u003e\u003cb\u003eKey Features \u0026amp; Research Applications\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color stronger tutor-markdown-rendering\" dir=\"ltr\"\u003e\u003cb\u003eTarget Binding Studies:\u003c\/b\u003e Evaluated for its binding interactions with the MH2 domain of Smad2, inhibiting downstream TGF-β-induced Smad2 phosphorylation \u003ci\u003ein vitro\u003c\/i\u003e.\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePreclinical Assays:\u003c\/b\u003e Investigated for suppressing fibrotic marker expression, collagen deposition, and connective tissue growth factor (CTGF) in fibroblast cultures.\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHigh Analytical Quality:\u003c\/b\u003e Verified via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm sequence precision.\u003c\/p\u003e\n\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp\u003e\u003cb\u003eStorage \u0026amp; Handling Guidelines\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReconstitution:\u003c\/b\u003e Dissolve in sterile analytical solvents or bacteriostatic water inside a certified laminar flow hood.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStorage (Unopened):\u003c\/b\u003e Store dry at \u003cb\u003e2°C to 8°C\u003c\/b\u003e for short-term preservation or \u003cb\u003e-20°C\u003c\/b\u003e for extended shelf life.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eStorage (Reconstituted):\u003c\/b\u003e Maintain liquid aliquots between \u003cb\u003e2°C to 8°C\u003c\/b\u003e and minimize freeze-thaw cycles.\u003c\/p\u003e","brand":"peptides ","offers":[{"title":"D","offer_id":46525633462468,"sku":null,"price":100.0,"currency_code":"MXN","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0751\/8424\/2884\/files\/product_3.jpg?v=1786743063","url":"https:\/\/peptidesvallarta.com\/products\/m10-trpasfwets","provider":"Peptides Vallarta","version":"1.0","type":"link"}