{"product_id":"ghrp-6-acetate","title":"GHRP-6 Acetate","description":"\u003ch1\u003e\n\u003cmeta charset=\"utf-8\"\u003eGHRP-6 Acetate 5 mg Research Peptide\u003c\/h1\u003e\n\u003cdiv dir=\"ltr\" align=\"left\"\u003e\n\u003ctable\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"180\"\u003e\n\u003ccol width=\"444\"\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAlternate name\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGrowth hormone releasing hexapeptide; SK\u0026amp;F-110679; hexapeptide-2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eCompound class\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSynthetic hexapeptide growth hormone secretagogue (GHS receptor agonist)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFormat\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eLyophilized powder (acetate salt) in a sealed vial\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eStrength(s)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e5 mg per vial\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSequence\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eHis-D-Trp-Ala-Trp-D-Phe-Lys-NH2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMolecular formula\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eC46H56N12O6 (free base)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMolecular weight\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e873.0 g\/mol (free base)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eCAS number\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e87616-84-0 (free base); 145177-42-0 (acetate, per PubChem)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eStated per lot on the Certificate of Analysis\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eManufacturer\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePEPTYVA, Mexico\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eWhat is GHRP-6 acetate?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThis listing is GHRP-6 acetate: 5 mg of growth hormone releasing hexapeptide in acetate salt form, made by PEPTYVA in Mexico. GHRP-6 is a synthetic peptide that stimulates growth hormone (GH) release. The vial is sold for laboratory research only; it is not a medicine and must not be used in humans or animals.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIts sequence is His-D-Trp-Ala-Trp-D-Phe-Lys-NH2, with D-tryptophan at position 2 and D-phenylalanine at position 5. It is among the older GH-releasing peptides, with endocrine studies in healthy men published in 1990.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eHow is GHRP-6 studied in research?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGHRP-6 is a classic tool for the growth hormone secretagogue receptor (GHS-R). The 1990 human study already proposed that its GH-releasing activity reflected a separate physiological system. In 1996, researchers cloned this G protein-coupled receptor from the pituitary and hypothalamus of swine and humans and showed that it was the target of the synthetic secretagogues. Its natural ligand, ghrelin, was identified in 1999.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eBecause it acts through this separate pathway, GHRP-6 is used to study how GH release is controlled independently of GHRH. Animal research has also examined links to feeding behavior: in a 1995 rat study, centrally given GHRP-6 was followed by eating, and the eating response did not track changes in plasma GH. These are rodent observations and do not describe effects in people.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eWhat does the current evidence show?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eHuman data for GHRP-6 are short endocrine measurements in small groups. In a 1990 study of 18 healthy men, GHRP-6 raised serum GH. Prolactin and cortisol rose about twofold only at the highest level tested, and LH and TSH did not change in the first hour.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eA 1992 study in five healthy men showed that the GH response to GHRP-6 persisted after the pituitary had been made unresponsive to GHRH, while the response to GHRH itself was lost. The authors concluded that the acute effect of GHRP-6 does not depend on endogenous GHRH.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThese studies measured hormones over hours. Efficacy for any use in people has not been established, and FDA notes possible effects on cortisol and blood glucose.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eHow does GHRP-6 differ from GHRP-2?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eBoth are hexapeptides that act on the same receptor, but their sequences and status differ. GHRP-6 begins with histidine and D-tryptophan, while GHRP-2 begins with D-alanine and D-2-naphthylalanine. GHRP-2, as pralmorelin, holds a Japanese approval as a diagnostic agent. For GHRP-6 we found no approved product in Drugs@FDA. GHRP-6 is also slightly heavier, at 873.0 g\/mol as the free base.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eWhat is the regulatory status of GHRP-6?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGHRP-6 is not an approved medicine in the US, and Drugs@FDA lists no product containing it. On September 29, 2023, FDA placed GHRP-6 in 503B Category 2, noting limited safety information, a risk of immunogenicity and concerns about cortisol and increased blood glucose due to lower insulin sensitivity. In Mexico, this vial is sold as research material only.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eOutside medicine regulation, anti-doping laboratories have published methods to detect GHRP-6 and its main metabolites in human urine, which reflects how closely its circulation is monitored.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eDocumentation\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eEach GHRP-6 acetate vial carries a PEPTYVA lot number. The Certificate of Analysis (COA) for that lot lists identity and purity, and states peptide content for the acetate salt. Ask for the COA through our contact page; Quality \u0026amp; Documentation explains each field.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eStorage and handling\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eLeave the 5 mg vial closed in its original box until laboratory use, shielded from direct light, humidity and heat and kept at the temperature on the PEPTYVA label.\u003c\/span\u003e\u003c\/p\u003e","brand":"Peptides Vallarta","offers":[{"title":"5 mg \/ c","offer_id":47106182316228,"sku":"PV-GHRP6-5MG","price":1060.0,"currency_code":"MXN","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0751\/8424\/2884\/files\/GHRP-6Acetate5mg.jpg?v=1792955828","url":"https:\/\/peptidesvallarta.com\/es\/products\/ghrp-6-acetate","provider":"Peptides Vallarta","version":"1.0","type":"link"}