{"product_id":"ghrp-2-acetate","title":"GHRP-2 Acetate","description":"\u003ch1 dir=\"ltr\"\u003e\u003cstrong\u003eGHRP-2 Acetate 5 mg Research Peptide (Pralmorelin)\u003c\/strong\u003e\u003c\/h1\u003e\n\u003cdiv dir=\"ltr\" align=\"left\"\u003e\n\u003ctable\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"180\"\u003e\n\u003ccol width=\"444\"\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAlternate name\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePralmorelin; KP-102; growth hormone releasing peptide-2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eCompound class\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSynthetic hexapeptide growth hormone secretagogue (GHS receptor agonist)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eFormat\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eLyophilized powder (acetate salt) in a sealed vial\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eStrength(s)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e5 mg per vial\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSequence\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eD-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMolecular formula\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eC45H55N9O6 (free base)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eMolecular weight\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e818.0 g\/mol (free base)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eCAS number\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003e158861-67-7 (free base)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePurity\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eStated per lot on the Certificate of Analysis\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eManufacturer\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePEPTYVA, Mexico\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eWhat is GHRP-2 acetate?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGHRP-2 acetate is the acetate salt of growth hormone releasing peptide-2, a synthetic hexapeptide with the nonproprietary name pralmorelin. This product is a 5 mg PEPTYVA vial for laboratory research use only. It is not a medicine and is not for human or veterinary use.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIts sequence is D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2. The two D-amino acids at the N-terminus, including the bulky D-2-naphthylalanine, set it apart from GHRP-6, which begins with histidine and D-tryptophan.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eSalt form changes the weight of each molecule. KEGG lists the dihydrochloride used in the Japanese product at 890.89 g\/mol, while PubChem gives 818.0 g\/mol for the free base. This vial is an acetate salt, so its net peptide content is defined on the lot Certificate of Analysis.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eHow is GHRP-2 studied in research?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGHRP-2 acts on the growth hormone secretagogue receptor (GHSR), which KEGG lists as its target. This receptor pathway is separate from the GHRH receptor, so GHRP-2 lets researchers probe GH release through a second route.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIts main use in people is as a diagnostic stimulus for pituitary GH reserve. A 2007 validation study enrolled 77 healthy adults and 58 adults with severe GH deficiency, defined by the insulin tolerance test, and examined how well the GH response to GHRP-2 separated the two groups. A 2013 Japanese study of 71 adults with pituitary tumors noted that the GHRP-2 test is one of the recommended alternatives to the insulin tolerance test in Japan.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eWhat does the current evidence show?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eGHRP-2's human data come mainly from diagnostic endocrine testing. In a 1995 randomized study in eight healthy men, GHRP-2 released more GH than GHRH(1-29) under the same test conditions.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eThe 2007 validation study reported that peak GH after GHRP-2 was far lower in adults with GH deficiency than in healthy adults, that the response was only mildly influenced by age and adiposity, and that repeat tests were reproducible. Those findings support diagnostic testing only. Outside diagnosis, evidence in people is limited and efficacy for other uses has not been established.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eHow does GHRP-2 differ from GHRP-6 and ipamorelin?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eAll three act on the same receptor, but GHRP-2 is the only one with a regulatory approval, as a Japanese diagnostic agent. In a 1998 comparison in conscious swine, GHRP-2 showed higher GH-releasing potency but a lower maximal GH response than GHRP-6 and ipamorelin. Like GHRP-6, and unlike ipamorelin, it also raised ACTH and cortisol in that model.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eWhat is the regulatory status of GHRP-2?\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003ePralmorelin is approved in Japan only as a diagnostic agent. KEGG DRUG lists pralmorelin hydrochloride (brand GHRP, Kaken Pharmaceutical) among Japanese new drug approvals dated October 22, 2004, classed as a diagnostic reagent for endocrine function. That approval belongs to the Japanese diagnostic product and does not extend to this research vial.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eIn the US, no GHRP-2 or pralmorelin product appears in Drugs@FDA. On September 29, 2023, FDA placed GHRP-2 in 503B Category 2, citing immunogenicity concerns and reports of serious adverse events, though causality has not been established.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eDocumentation\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eEvery GHRP-2 acetate vial is printed with a PEPTYVA lot number. Because the product is a salt, the lot's Certificate of Analysis (COA) is the place to check identity, purity and peptide content. Request it through our contact page.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 dir=\"ltr\"\u003e\u003cstrong\u003eStorage and handling\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp dir=\"ltr\"\u003e\u003cspan\u003eStore the unopened 5 mg vial sealed in its original packaging, away from light, humidity and heat, at the temperature printed on the PEPTYVA label. Verify the seal and lot number when it arrives.\u003c\/span\u003e\u003c\/p\u003e","brand":"Peptides Vallarta","offers":[{"title":"5 mg \/ C","offer_id":47106182250692,"sku":"PV-GHRP2-5MG","price":1060.0,"currency_code":"MXN","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0751\/8424\/2884\/files\/GHRP-2Acetate5mg.jpg?v=1792955503","url":"https:\/\/peptidesvallarta.com\/es\/products\/ghrp-2-acetate","provider":"Peptides Vallarta","version":"1.0","type":"link"}